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Faster chemo boosts survival from type of nerve cancer

Posted on Mon, February 25, 2008 at 10:00PM by Registered CommenterNeil Hutchison | Comments13 Comments | References3 References

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It looks like this study accounts for two changes simultaneously which clouds the results. They increased the treatment dosage by 80% ("1.8 times the conventional dose") AND they decreased the treatment interval. Do I read this right?

Is there existing data on the affectivity of just increasing the dose that could account for some of the 12% benefit cited? If so, does that study also cite the detriments of dose increase as well?

Just a few comments/questions to discuss. This does look promising, though.

February 26, 2008 | Unregistered CommenterBrian Dumaine

It is counter-intuitive that they would decrease the interval while increasing the dose. Nevertheless, nice to see researchers messing with timing a bit.

One of the other MagicWater founders, Neil, had emailed Dr. Hrushesky to see if his lab would have time to do a chronobiology study funded by MagicWater. He unfortunately focuses on adult cancers and so declined Neil's offer.

See additions following the original post for some interesting reading on chronotherapy.

February 26, 2008 | Unregistered CommenterAndy Mikulak

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